SCHEMBL8565173

CCOC(=O)c1cccc(NC(=O)NCC(=O)N(C)c2ccc(Cl)c(COc3cccn4c(Br)c(C)nc34)c2Cl)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	BDKRB2	P30411	19/20	1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Hydrochloric Acid SCHEMBL8560916	0.99	BDKRB2 (0.99)	BDKRB2
SCHEMBL8561594	0.95	BDKRB2 (1.00)	BDKRB2
Hydrochloric Acid SCHEMBL8564361	0.94	BDKRB2 (1.00)	BDKRB2
SCHEMBL8558714	0.94	BDKRB2 (1.00)	BDKRB2
Hydrochloric Acid SCHEMBL8566586	0.93	BDKRB2 (0.99)	BDKRB2
SCHEMBL8566782	0.93	BDKRB2 (1.00)	BDKRB2
Hydrochloric Acid SCHEMBL8564207	0.93	BDKRB2 (1.00)	BDKRB2
SCHEMBL8564680	0.93	BDKRB2 (0.86)	BDKRB2
Hydrochloric Acid SCHEMBL8566913	0.92	BDKRB2 (0.86)	BDKRB2
SCHEMBL8559745	0.92	BDKRB2 (1.00)	BDKRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0596406-B1	Imidazo (1,2-a) Pyridines as bradykinin antagonists	FUJISAWA PHARMACEUTICAL CO (JP)	1998-12-16	—	—	EP	disclosed
US-5574042-A	ANTAGONIST FOR BRADYKININS AS ANTIALLERGENS, AUTOIMMUNE DISEASES, ANTIINFLAMMATORY AGENTS, SHOCK OR PAIN	FUJISAWA PHARMACEUTICAL CO., LTD (JP)	1996-11-12	—	—	US	disclosed
EP-0596406-A1	Imidazo (1,2-a) Pyridines as bradykinin antagonists	FUJISAWA PHARMACEUTICAL CO., LTD. (JP)	1994-05-11	—	—	EP	disclosed