Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | ASPH | Q12797 | 2/20 | 0.42 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | AGER | Q15109 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562662 | 0.86 | KDM4E (0.39) | KDM4EASPHKDM8TDP1ALDH1A1 | |
| SCHEMBL8561746 | 0.85 | PDE3B (0.40) | KDM4ETDP1ALDH1A1LMNAMEN1 | |
| SCHEMBL31693360 | 0.82 | ASPH (0.55) | KDM4EASPHKDM8TDP1ALDH1A1 | |
| SCHEMBL15758083 | 0.82 | ASPH (0.55) | KDM4EASPHKDM8TDP1ALDH1A1 | |
| SCHEMBL28153684 | 0.81 | KDM4E (0.43) | KDM4EASPHKDM8TDP1ALDH1A1 | |
| SCHEMBL11734394 | 0.81 | KDM4E (0.49) | KDM4EASPHKDM8TDP1ALDH1A1 | |
| SCHEMBL27364920 | 0.80 | HTR2A (0.39) | KDM4EASPHKDM8ALDH1A1CYP3A4 | |
| SCHEMBL8567354 | 0.79 | HTT (0.40) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL8565828 | 0.79 | MAPT (0.39) | KDM4EASPHKDM8TDP1ALDH1A1 | |
| SCHEMBL2009352 | 0.77 | KMT2A (0.50) | KDM4EASPHKDM8TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |