Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 5/20 | 0.34 |
| ▸ | CA1 | P00915 | 5/20 | 0.34 |
| ▸ | CA2 | P00918 | 5/20 | 0.34 |
| ▸ | CA9 | Q16790 | 5/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560363 | 0.88 | CA12 (0.42) | LMNATHRBCYP2C19CA12CA1 | |
| SCHEMBL8557711 | 0.86 | LMNA (0.39) | LMNATHRBCYP2C19CA12CA1 | |
| SCHEMBL6537369 | 0.86 | CA12 (0.40) | LMNATHRBCYP2C19CA12CA1 | |
| SCHEMBL6131614 | 0.84 | LMNA (0.52) | LMNATHRBCYP2C19CA12CA1 | |
| SCHEMBL6131605 | 0.82 | CA12 (0.46) | LMNATHRBCYP2C19CA12CA1 | |
| SCHEMBL8478713 | 0.81 | LMNA (0.51) | LMNATHRBCYP2C19CA12CA1 | |
| SCHEMBL6131569 | 0.80 | LMNA (0.55) | LMNATHRBCYP2C19CA12CA1 | |
| SCHEMBL6131660 | 0.78 | CA12 (0.48) | LMNATHRBCYP2C19CA12CA1 | |
| SCHEMBL8716992 | 0.77 | CA12 (0.38) | LMNATHRBCYP2C19CA12CA1 | |
| SCHEMBL8473394 | 0.77 | LMNA (0.55) | LMNATHRBCYP2C19CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808091-A | DIAGNOSTIC IMAGING AGENT | BRACCO INTERNATIONAL B.V. | 1998-09-15 | — | — | US | disclosed |
| US-5688487-A | Diagnostic imaging methods using rhenium and technetium complexes containing a hypoxia-localizing moiety | BRACCO INTERNATIONAL B.V. (NL) | 1997-11-18 | — | — | US | disclosed |