Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 4/20 | 0.33 |
| ▸ | MMP1 | P03956 | 4/20 | 0.33 |
| ▸ | MMP2 | P08253 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | MMP8 | P22894 | 3/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ESRRB | O95718 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8565444 | 1.00 | SMN1; SMN2 (0.38) | SMN1; SMN2CA14CA12MMP1MMP2 | |
| SCHEMBL8558146 | 1.00 | SMN1; SMN2 (0.38) | SMN1; SMN2CA14CA12MMP1MMP2 | |
| SCHEMBL2403902 | 0.84 | GABRR1 (0.39) | SMN1; SMN2CA14CA12MMP1MMP2 | |
| SCHEMBL5456859 | 0.82 | MMP1 (0.38) | SMN1; SMN2CA14CA12MMP1MMP2 | |
| SCHEMBL2466027 | 0.82 | MMP1 (0.38) | SMN1; SMN2CA14CA12MMP1MMP2 | |
| SCHEMBL8558408 | 0.80 | SMN1; SMN2 (0.37) | SMN1; SMN2CA14CA12MMP1MMP2 | |
| SCHEMBL8558409 | 0.80 | SMN1; SMN2 (0.37) | SMN1; SMN2CA14CA12MMP1MMP2 | |
| SCHEMBL15259072 | 0.78 | MMP1 (0.35) | SMN1; SMN2CA14CA12MMP1MMP2 | |
| SCHEMBL2352012 | 0.77 | MMP1 (0.38) | SMN1; SMN2CA14CA12MMP1MMP2 | |
| SCHEMBL9697205 | 0.75 | ANPEP (0.35) | SMN1; SMN2CA12MMP1MMP2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739373-A | Optically active phosphono analogs of succinates and synthesis thereof | MONSANTO COMPANY (US) | 1998-04-14 | — | — | US | disclosed |
| US-5473092-A | Synthesis of optically-active phosphono analogs of succinates | MONSANTO COMPANY (US) | 1995-12-05 | — | — | US | disclosed |