Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.53 |
| ▸ | DRD3 | P35462 | 4/20 | 0.53 |
| ▸ | PNMT | P11086 | 6/20 | 0.49 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14896444 | 0.92 | PNMT (0.53) | DRD2DRD3PNMTKDM1ACYP19A1 | |
| SCHEMBL1786744 | 0.84 | PNMT (0.50) | DRD2DRD3PNMTKDM1ATRPA1 | |
| SCHEMBL29741121 | 0.75 | PNMT (0.60) | DRD2DRD3PNMTKDM1ACYP19A1 | |
| SCHEMBL29618357 | 0.75 | PNMT (0.60) | DRD2DRD3PNMTKDM1ACYP19A1 | |
| SCHEMBL8222195 | 0.75 | PNMT (0.60) | DRD2DRD3PNMTKDM1ACYP19A1 | |
| SCHEMBL3363261 | 0.75 | PNMT (0.60) | DRD2DRD3PNMTKDM1ACYP19A1 | |
| Hydrochloric Acid SCHEMBL15205820 | 0.74 | PNMT (0.58) | DRD2DRD3PNMTKDM1ACYP19A1 | |
| Hydrochloric Acid SCHEMBL30894888 | 0.74 | PNMT (0.58) | DRD2DRD3PNMTKDM1ACYP19A1 | |
| SCHEMBL17350029 | 0.74 | PNMT (0.58) | DRD2DRD3PNMTKDM1ACYP19A1 | |
| SCHEMBL4033305 | 0.72 | PNMT (0.79) | DRD2DRD3PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110590708-B | Aroyl piperazine compound, preparation method thereof and application thereof in antivirus | 中国医学科学院医药生物技术研究所 | 2021-08-17 | — | — | CN | claimed |
| CN-110590708-A | Aroyl piperazine compound, preparation method thereof and application thereof in antivirus | 中国医学科学院医药生物技术研究所 | 2019-12-20 | — | — | CN | claimed |
| CN-110590708-B | Aroyl piperazine compound, preparation method thereof and application thereof in antivirus | 中国医学科学院医药生物技术研究所 | 2021-08-17 | — | — | CN | disclosed |
| CN-110590708-A | Aroyl piperazine compound, preparation method thereof and application thereof in antivirus | 中国医学科学院医药生物技术研究所 | 2019-12-20 | — | — | CN | disclosed |
| EP-2952096-B1 | Amide compound, an arthropod pest control agent and a method for controlling arthropod pest | SUMITOMO CHEMICAL CO (JP) | 2018-04-04 | — | — | EP | disclosed |
| US-9814235-B2 | Method for controlling arthropod pest | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-11-14 | — | — | US | disclosed |
| EP-2952096-A1 | METHOD FOR CONTROLLING ARTHROPOD PEST | Sumitomo Chemical Company, Limited (JP) | 2015-12-09 | — | — | EP | disclosed |
| US-20150344466-A1 | METHOD FOR CONTROLLING ARTHROPOD PEST | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-12-03 | — | — | US | disclosed |
| EP-0431943-B1 | Spiro(pyran)piperidine derivatives | MERCK & CO INC (US) | 1998-07-15 | — | — | EP | disclosed |
| US-5633247-A | ANTIARRTHYMIA AGENT | MERCK & CO., INC. (US) | 1997-05-27 | — | — | US | disclosed |
| EP-0683782-A4 | SPIRO (2H-1-BENZOPYRAN-2, 4' PIPERIDINE) CLASS III ANTIARRHYTHMICS. | MERCK & CO INC (US) | 1996-03-27 | — | — | EP | disclosed |
| EP-0683782-A1 | SPIRO (2H-1-BENZOPYRAN-2, 4' PIPERIDINE) CLASS III ANTIARRHYTHMICS | MERCK & CO. INC. (US) | 1995-11-29 | — | — | EP | disclosed |
| WO-1994018204-A1 | SPIRO (2H-1-BENZOPYRAN-2, 4' PIPERIDINE) CLASS III ANTIARRHYTHMICS | MERCK & CO., INC. (US) | 1994-08-18 | — | — | WO | disclosed |
| US-5206240-A | Antiarrhythmia agents | MERCK & CO., INC. (US) | 1993-04-27 | — | — | US | disclosed |
| EP-0431943-A2 | Nitrogen-containing spirocycles | MERCK & CO. INC. (US) | 1991-06-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150344466-A1 | METHOD FOR CONTROLLING ARTHROPOD PEST | H1-0, H1-3, H1-2 | DRD2 923/4885DRD3 213/4885PNMT 453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.