Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 3/20 | 0.35 |
| ▸ | CCR5 | P51681 | 3/20 | 0.35 |
| ▸ | CCR8 | P51685 | 3/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GPR39 | O43194 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F12 | P00748 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8565890 | 0.75 | CCR1 (0.38) | SYKALDH1A1RAB9ACCR1CCR5 | |
| SCHEMBL30551751 | 0.72 | KDM4E (0.48) | ALDH1A1RAB9ACCR1CCR5CCR8 | |
| SCHEMBL5089682 | 0.72 | KDM4E (0.48) | ALDH1A1RAB9ACCR1CCR5CCR8 | |
| SCHEMBL8571537 | 0.71 | KDM4E (0.41) | RAB9ACCR1CCR5CCR8HSP90AA1 | |
| Iodide SCHEMBL8962203 | 0.70 | KDM4E (0.46) | ALDH1A1RAB9ACCR1CCR5CCR8 | |
| SCHEMBL7644327 | 0.68 | TDP1 (0.44) | ALDH1A1L3MBTL1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL4581614 | 0.68 | CCR1 (0.56) | ALDH1A1RAB9ACCR1CCR5CCR8 | |
| SCHEMBL28320230 | 0.65 | KDM4E (0.43) | ALDH1A1RAB9ACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL10772309 | 0.65 | KDM4E (0.70) | ALDH1A1RAB9ACCR1CCR5CCR8 | |
| SCHEMBL4583539 | 0.64 | KDM4E (0.42) | ALDH1A1RAB9ACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758337-B1 | PHOSPHONATED POLYPYRIDYL COMPOUNDS AND THEIR COMPLEXES | ECOLE POLYTECH (CH) | 1998-12-16 | — | — | EP | disclosed |
| US-5789592-A | Phosphonated polypyridyl compounds and their complexes | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (CH) | 1998-08-04 | — | — | US | disclosed |
| EP-0758337-A1 | PHOSPHONATED POLYPYRIDYL COMPOUNDS AND THEIR COMPLEXES | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (CH) | 1997-02-19 | — | — | EP | disclosed |
| WO-1995029924-A1 | PHOSPHONATED POLYPYRIDYL COMPOUNDS AND THEIR COMPLEXES | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 1995-11-09 | — | — | WO | disclosed |