Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 3/20 | 0.38 |
| ▸ | CCR5 | P51681 | 3/20 | 0.38 |
| ▸ | CCR8 | P51685 | 3/20 | 0.38 |
| ▸ | SYK | P43405 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28320230 | 0.80 | KDM4E (0.43) | CCR1CCR5CCR8KDM4EHSP90AA1 | |
| SCHEMBL4581614 | 0.80 | CCR1 (0.56) | CCR1CCR5CCR8KDM4EHSP90AA1 | |
| SCHEMBL3884850 | 0.79 | KDM4E (0.42) | CCR1CCR5CCR8KDM4EHSP90AA1 | |
| SCHEMBL8565884 | 0.75 | SYK (0.35) | CCR1CCR5CCR8SYKKDM4E | |
| SCHEMBL8571537 | 0.71 | KDM4E (0.41) | CCR1CCR5CCR8KDM4EHSP90AA1 | |
| SCHEMBL12669547 | 0.71 | KDM4E (0.54) | CCR1CCR5CCR8KDM4EHSP90AA1 | |
| SCHEMBL23037082 | 0.69 | CCR1 (0.46) | CCR1CCR5CCR8KDM4EHSP90AA1 | |
| SCHEMBL12131299 | 0.68 | ADORA3 (0.44) | CCR1CCR5CCR8KDM4EHSP90AA1 | |
| Hydrochloric Acid SCHEMBL5098652 | 0.68 | CCR1 (0.45) | CCR1CCR5CCR8KDM4EHSP90AA1 | |
| SCHEMBL16215309 | 0.67 | CCR1 (0.58) | CCR1CCR5CCR8KDM4EHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758337-B1 | PHOSPHONATED POLYPYRIDYL COMPOUNDS AND THEIR COMPLEXES | ECOLE POLYTECH (CH) | 1998-12-16 | — | — | EP | disclosed |
| US-5789592-A | Phosphonated polypyridyl compounds and their complexes | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (CH) | 1998-08-04 | — | — | US | disclosed |
| EP-0758337-A1 | PHOSPHONATED POLYPYRIDYL COMPOUNDS AND THEIR COMPLEXES | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (CH) | 1997-02-19 | — | — | EP | disclosed |
| WO-1995029924-A1 | PHOSPHONATED POLYPYRIDYL COMPOUNDS AND THEIR COMPLEXES | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 1995-11-09 | — | — | WO | disclosed |