SCHEMBL8565976

SCHEMBL8565976

Nc1c([N+](=O)[O-])nc2ccccc2c1C=Cc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 1/20 0.42
ELANE P08246 1/20 0.41
TUBB4A P04350 1/20 0.41
TUBB P07437 1/20 0.41
TUBA3C P0DPH7 1/20 0.41
TUBA1B P68363 1/20 0.41
TUBA4A P68366 1/20 0.41
TUBB4B P68371 1/20 0.41
TUBB3 Q13509 1/20 0.41
TUBB2A Q13885 1/20 0.41
TUBB8 Q3ZCM7 1/20 0.41
TUBA3E Q6PEY2 1/20 0.41
TUBA1A Q71U36 1/20 0.41
TUBA1C Q9BQE3 1/20 0.41
TUBB6 Q9BUF5 1/20 0.41
TUBB2B Q9BVA1 1/20 0.41
TUBB1 Q9H4B7 1/20 0.41
KMT2A Q03164 2/20 0.41
RAB9A P51151 6/20 0.41
NPC1 O15118 4/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8567364 0.86 KDM4E (0.40) KMT2ARAB9ANPC1MAPTSMN1; SMN2
SCHEMBL8567366 0.86 KDM4E (0.40) KMT2ARAB9ANPC1MAPTSMN1; SMN2
SCHEMBL8562134 0.82 NFE2L2 (0.41) NFE2L2ELANETUBB4ATUBBTUBA3C
SCHEMBL8566394 0.80 POLB (0.38) KMT2ARAB9ANPC1MAPTSMN1; SMN2
SCHEMBL8566398 0.80 POLB (0.38) KMT2ARAB9ANPC1MAPTSMN1; SMN2
SCHEMBL8564523 0.80 KDM4E (0.53) ELANEKMT2ARAB9AMAPTSMN1; SMN2
SCHEMBL8561932 0.77 KDM4E (0.46) KMT2ARAB9AMAPTSMN1; SMN2HTT
SCHEMBL8560906 0.77 TAAR1 (0.46) NFE2L2ELANETUBB4ATUBBTUBA3C
SCHEMBL5271563 0.77 MAPT (0.59) NFE2L2KMT2ARAB9ANPC1MAPT
SCHEMBL5276926 0.77 MAPT (0.59) NFE2L2KMT2ARAB9ANPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0735025-B1 Process for producing aminonitropyridines SUMITOMO CHEMICAL CO (JP) 1998-07-01 EP disclosed
US-5648496-A AMINATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-07-15 US disclosed
EP-0735025-A1 Process for producing aminonitropyridines SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-10-02 EP disclosed