Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | RHEB | Q15382 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17536018 | 0.88 | S1PR4 (0.52) | PTGER1SMN1; SMN2MAPTTDP1L3MBTL1 | |
| SCHEMBL6883736 | 0.83 | MAPK14 (0.43) | PTGER1SMN1; SMN2MAPTTDP1L3MBTL1 | |
| SCHEMBL28848218 | 0.79 | MAPT (0.46) | PTGER1SMN1; SMN2MAPTTDP1L3MBTL1 | |
| SCHEMBL30522860 | 0.79 | MAPT (0.46) | PTGER1SMN1; SMN2MAPTTDP1L3MBTL1 | |
| SCHEMBL3400984 | 0.78 | CYP4F2 (0.44) | CYP4F2CYP4A11PTGER1SMN1; SMN2MAPT | |
| SCHEMBL6639600 | 0.78 | MAPT (0.44) | PTGER1SMN1; SMN2MAPTTDP1L3MBTL1 | |
| SCHEMBL16740982 | 0.76 | PTGER1 (0.58) | PTGER1POLBFOLH1CHRM4CHRM3 | |
| SCHEMBL17535463 | 0.75 | MAPK1 (0.41) | PTGER1SMN1; SMN2MAPTCYP2C9CYP2C19 | |
| SCHEMBL19127410 | 0.74 | PRMT5 (0.55) | PTGER1SMN1; SMN2MAPTCYP2C9CYP2C19 | |
| SCHEMBL6638380 | 0.74 | MAPK1 (0.48) | PTGER1SMN1; SMN2MAPTCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0824524-A1 | ALPHA-SUBSTITUTED PYRIMIDINE-THIOALKYL AND ALKYLETHER COMPOUNDS AS INHIBITORS OF VIRAL REVERSE TRANSCRIPTASE | PHARMACIA & UPJOHN COMPANY (US) | 1998-02-25 | — | — | EP | disclosed |