Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.48 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8568441 | 0.88 | MAOB (0.54) | MAOBNR1H4 | |
| SCHEMBL8560924 | 0.87 | NR1H4 (0.46) | MAOBNR1H4PLA2G2DCYSLTR2CYSLTR1 | |
| SCHEMBL26455227 | 0.83 | MAOB (0.60) | MAOBCYSLTR2CYSLTR1 | |
| SCHEMBL9074308 | 0.80 | NR1H4 (0.46) | MAOBNR1H4PLA2G2D | |
| SCHEMBL26455225 | 0.80 | MAOB (0.64) | MAOB | |
| SCHEMBL6760986 | 0.79 | MAOB (0.61) | MAOB | |
| SCHEMBL6899074 | 0.78 | MAOB (0.65) | MAOB | |
| SCHEMBL6756014 | 0.77 | NR4A2 (0.47) | MAOB | |
| SCHEMBL9324047 | 0.77 | PTPN11 (0.58) | MAOB | |
| SCHEMBL8562415 | 0.77 | MAOB (0.52) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544488-B1 | Substituted phenyl phenol leukotriene antagonists | LILLY CO ELI (US) | 1998-03-11 | — | — | EP | disclosed |
| WO-1996036347-A1 | USE OF LEUKOTRIENE ANTAGONISTS FOR ALZHEIMER'S DISEASE | ELI LILLY AND COMPANY (US) | 1996-11-21 | — | — | WO | disclosed |
| EP-0743064-A1 | Leukotriene antagonists for use in the treatment or prevention of alzheimer's disease | ELI LILLY AND COMPANY (US) | 1996-11-20 | — | — | EP | disclosed |
| US-5462954-A | Antiinflammatory, antiallergens; treating asthma | ELI LILLY AND COMPANY (US) | 1995-10-31 | — | — | US | disclosed |
| EP-0544488-A2 | Substituted phenyl phenol leukotriene antagonists | ELI LILLY AND COMPANY (US) | 1993-06-02 | — | — | EP | disclosed |