Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | CALML3 | P27482 | 1/20 | 0.45 |
| ▸ | SDHA | P31040 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 7/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8802258 | 1.00 | MAOA (0.49) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL8802647 | 0.91 | MAOA (0.40) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL8564138 | 0.91 | MAOA (0.40) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL8563892 | 0.85 | MAOA (0.46) | MAOAMAOBCALML3F10 | |
| SCHEMBL8801479 | 0.85 | MAOA (0.46) | MAOAMAOBCALML3F10 | |
| SCHEMBL8801297 | 0.84 | F10 (0.40) | MAOAMAOBF10 | |
| Hydrochloric Acid SCHEMBL8559952 | 0.83 | F10 (0.39) | MAOAMAOBF10 | |
| SCHEMBL8802028 | 0.81 | MAOA (0.46) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL8802252 | 0.79 | MAOA (0.52) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL8565047 | 0.78 | GRM2 (0.35) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827857-A | BACTERICIDES AND MICROBIOCIDES; GRAMPOSITIVE BACTERIA, HEMOPHILUS INFLUENZA, ANAEROBIC MICROORGANISMS AND MYCOBACTERIA; LOW TOXICITY | BAYER AKTIENGESELLSCHAFT (DE) | 1998-10-27 | — | — | US | disclosed |