SCHEMBL8566384

SCHEMBL8566384

Cc1ccc(CC(Br)Br)cc1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.46
CYP1A2 P05177 1/20 0.42
CYP2A6 P11509 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42
ACHE P22303 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
AGXT P21549 2/20 0.41
ALDH1A1 P00352 1/20 0.39
ACACB O00763 1/20 0.37
PPARG P37231 1/20 0.36
PPARA Q07869 1/20 0.36
CHRM2 P08172 1/20 0.35
TP53 P04637 1/20 0.35
MAPT P10636 1/20 0.35
CYP19A1 P11511 1/20 0.35
NR3C1 P04150 1/20 0.35
PGR P06401 1/20 0.35
NR3C2 P08235 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10724758 0.86 SLC6A4 (0.38) TAAR1
SCHEMBL29018029 0.82 IDO1 (0.44) IDO1CYP1A2CYP2A6TAAR1ACHE
SCHEMBL7643271 0.82 IDO1 (0.44) IDO1CYP1A2CYP2A6TAAR1ACHE
SCHEMBL9790105 0.82 IDO1 (0.44) IDO1CYP1A2CYP2A6TAAR1ACHE
SCHEMBL6425532 0.80 IDO1 (0.42) IDO1CYP1A2CYP2A6TAAR1ACHE
SCHEMBL196656 0.76 PTGS1 (0.48) IDO1CYP1A2CYP2A6TAAR1ACHE
SCHEMBL5496261 0.76 PTGS1 (0.48) IDO1CYP1A2CYP2A6TAAR1ACHE
SCHEMBL6832904 0.75 IDO1 (0.42) IDO1CYP1A2CYP2A6TAAR1ACHE
SCHEMBL24017123 0.74 TAAR1 (0.48) IDO1CYP1A2CYP2A6TAAR1ACHE
SCHEMBL607203 0.74 IDO1 (0.46) IDO1CYP1A2CYP2A6TAAR1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3891229-A1 PROCESS FOR PREPARING A SURFACE WITH BACTERIOSTATIC ACTIVITY AND SURFACE THUS PREPARED Commissariat à l'énergie atomique et aux énergies alternatives (FR) 2021-10-13 EP disclosed
WO-2020115434-A1 PROCESS FOR PREPARING A SURFACE WITH BACTERIOSTATIC ACTIVITY AND SURFACE THUS PREPARED COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2020-06-11 WO disclosed
US-5763649-A Process for producing aromatic carboxylic acids MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1998-06-09 US disclosed
EP-0818433-A2 Process for producing aromatic carboxylic acids MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1998-01-14 EP disclosed