Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564093 | 1.00 | EPHX2 (0.47) | EPHX2RENMTNR1AMTNR1BNAMPT | |
| SCHEMBL8564090 | 1.00 | EPHX2 (0.47) | EPHX2RENMTNR1AMTNR1BNAMPT | |
| SCHEMBL7003843 | 0.94 | EPHX2 (0.54) | EPHX2RENMTNR1AMTNR1BNAMPT | |
| SCHEMBL12679645 | 0.84 | EPHX2 (0.54) | EPHX2RENMTNR1AMTNR1BNAMPT | |
| SCHEMBL7006038 | 0.84 | EPHX2 (0.54) | EPHX2RENMTNR1AMTNR1BNAMPT | |
| SCHEMBL2489959 | 0.81 | EPHX2 (0.51) | EPHX2MTNR1AMTNR1BNAMPTKDM1A | |
| SCHEMBL1448032 | 0.80 | NAMPT (0.46) | RENNAMPTKDM1AHDAC1HDAC6 | |
| SCHEMBL16353535 | 0.79 | NOTUM (0.47) | NAMPTKDM1AHDAC1HDAC6BCHE | |
| SCHEMBL16353667 | 0.79 | NOTUM (0.47) | NAMPTKDM1AHDAC1HDAC6BCHE | |
| SCHEMBL16385108 | 0.79 | NOTUM (0.47) | NAMPTKDM1AHDAC1HDAC6BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719141-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1998-02-17 | — | — | US | disclosed |