Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL924887 | 1.00 | HPGD (0.61) | HPGDALDH1A1CYP4F2CYP4A11POLB | |
| SCHEMBL8566458 | 1.00 | HPGD (0.61) | HPGDALDH1A1CYP4F2CYP4A11POLB | |
| Hydrochloric Acid SCHEMBL11567507 | 0.99 | HPGD (0.60) | HPGDALDH1A1CYP4F2CYP4A11POLB | |
| SCHEMBL26940175 | 0.89 | HPGD (0.62) | HPGDALDH1A1HSD17B10KDM4EKMT2A | |
| SCHEMBL8562493 | 0.84 | HPGD (0.61) | HPGDALDH1A1HSD17B10KDM4EMEN1 | |
| SCHEMBL8562494 | 0.84 | HPGD (0.61) | HPGDALDH1A1HSD17B10KDM4EMEN1 | |
| SCHEMBL1689603 | 0.84 | HPGD (0.61) | HPGDALDH1A1HSD17B10KDM4EMEN1 | |
| SCHEMBL11561148 | 0.84 | ADAMTS5 (0.46) | HPGDALDH1A1CYP4F2CYP4A11POLB | |
| SCHEMBL7817820 | 0.84 | HSD17B10 (0.60) | HPGDALDH1A1CYP4F2CYP4A11POLB | |
| SCHEMBL2577554 | 0.84 | HSD17B10 (0.48) | HPGDALDH1A1CYP4F2CYP4A11POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719141-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1998-02-17 | — | — | US | disclosed |
| EP-0702004-A2 | 2,9-diamino- and 2-amino-8-carbamoyl-4-hydroxy-alkanoic acid amid derivatives | CIBA-GEIGY AG (CH) | 1996-03-20 | — | — | EP | disclosed |