SCHEMBL8566480

SCHEMBL8566480

CCCC=CCCCCc1ccnc(-c2ccc(CCCCCC(C)OC3CCCCO3)cc2)n1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SPHK2 Q9NRA0 8/20 0.31
SPHK1 Q9NYA1 6/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8566485 0.86
SCHEMBL8670843 0.81 KDM4E (0.40) SPHK2SPHK1
SCHEMBL8566595 0.78 ASAH2 (0.38) SPHK2SPHK1
SCHEMBL8564925 0.76 RAB9A (0.37) SPHK2SPHK1
SCHEMBL8602508 0.71 MEN1 (0.33)
SCHEMBL23387073 0.69
SCHEMBL21625761 0.69
SCHEMBL23387049 0.69 MEN1 (0.30)
SCHEMBL10062397 0.67
SCHEMBL13265996 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0667384-B1 Fluorine-containing optically active compound, process for preparing the same and liquid crystal mixture and liquid crystal element comprising the same SUMITOMO CHEMICAL CO (JP) 1998-12-16 EP disclosed
US-5779934-A FLUORINATING AN ALCOHOL DERIVATIVE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-07-14 US disclosed
EP-0667384-A1 Fluorine-containing optically active compound, process for preparing the same and liquid crystal mixture and liquid crystal element comprising the same SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-08-16 EP disclosed