Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 15/20 | 0.51 |
| ▸ | CA2 | P00918 | 15/20 | 0.51 |
| ▸ | CA9 | Q16790 | 15/20 | 0.51 |
| ▸ | CA1 | P00915 | 14/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 12/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8758650 | 0.86 | MEN1 (0.53) | CA12CA2CA9CA1CA14 | |
| SCHEMBL8562782 | 0.82 | KMT2A (0.43) | CA2CA1MEN1KMT2A | |
| SCHEMBL5700184 | 0.82 | KMT2A (0.43) | CA12CA2CA9CA1CA14 | |
| SCHEMBL27462207 | 0.80 | MAPT (0.43) | CA12CA2CA9CA1CA14 | |
| SCHEMBL8598731 | 0.74 | ALDH1A1 (0.40) | CA12CA2CA9CA1CA14 | |
| SCHEMBL8568179 | 0.74 | ALDH1A1 (0.53) | MEN1KMT2ALMNA | |
| SCHEMBL8567922 | 0.73 | ALDH1A1 (0.57) | CA12CA2CA9CA1CA14 | |
| SCHEMBL2602388 | 0.73 | ALDH1A1 (0.50) | MEN1KMT2ALMNA | |
| SCHEMBL29547967 | 0.73 | ALDH1A1 (0.49) | MEN1KMT2ALMNA | |
| SCHEMBL1284068 | 0.73 | MAPT (0.53) | MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |