Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 6/20 | 0.38 |
| ▸ | CA2 | P00918 | 6/20 | 0.38 |
| ▸ | CA12 | O43570 | 5/20 | 0.38 |
| ▸ | CA9 | Q16790 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559697 | 0.83 | APEX1 (0.51) | APEX1PRMT1KDM4ECA1CA2 | |
| SCHEMBL10901189 | 0.80 | APEX1 (0.68) | APEX1PRMT1CA1CA2CA12 | |
| SCHEMBL9352747 | 0.80 | CA2 (0.47) | APEX1KDM4ECA1CA2CA12 | |
| SCHEMBL9319491 | 0.78 | APEX1 (0.67) | APEX1PRMT1MEN1KMT2ANT5E | |
| SCHEMBL8752069 | 0.78 | APEX1 (0.67) | APEX1MEN1KMT2ANT5EENPP2 | |
| SCHEMBL10874471 | 0.74 | APEX1 (0.60) | APEX1PRMT1KDM4EMEN1KMT2A | |
| SCHEMBL11139178 | 0.74 | APEX1 (0.61) | APEX1PRMT1KDM4ECA1CA2 | |
| SCHEMBL9145883 | 0.74 | APEX1 (0.64) | APEX1PRMT1MEN1KMT2ATHRB | |
| SCHEMBL18920877 | 0.73 | APEX1 (0.74) | APEX1PRMT1KDM4EMEN1KMT2A | |
| SCHEMBL9795462 | 0.73 | APEX1 (0.70) | APEX1KDM4EKMT2ACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5834601-A | DYEING CELLULOSE, WOOL, POLYAMIDE | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 1998-11-10 | — | — | US | disclosed |