Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | CCR6 | P51684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30033168 | 0.75 | — | — | |
| SCHEMBL6251930 | 0.67 | MAPT (0.33) | MAPTALDH1A1KMT2AMEN1POLB | |
| SCHEMBL9139763 | 0.66 | ATM (0.41) | MAPTALDH1A1KMT2AMEN1POLB | |
| SCHEMBL29161382 | 0.65 | MAPT (0.54) | MAPTALDH1A1KMT2AMEN1POLB | |
| SCHEMBL16597318 | 0.63 | MEN1 (0.30) | ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL1137916 | 0.62 | MAPT (0.40) | MAPTALDH1A1KMT2AMEN1POLB | |
| SCHEMBL5855550 | 0.62 | MAPT (0.40) | MAPTALDH1A1KMT2AMEN1POLB | |
| Isatin SCHEMBL7073534 | 0.62 | MAPT (0.47) | MAPTALDH1A1KMT2AMEN1POLB | |
| SCHEMBL8525118 | 0.62 | MAPT (0.35) | MAPTALDH1A1KMT2AMEN1POLB | |
| SCHEMBL2565507 | 0.62 | MAPT (0.35) | MAPTALDH1A1KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4497438-A2 | TRICYCLIC PARP1 INHIBITORS AND USES THEREOF | Xinthera, Inc. (US) | 2025-01-29 | — | — | EP | disclosed |
| EP-0853622-A1 | PROCESS FOR PREPARING 1-ARYL-4-OXOPYRROLO 3,2-c]QUINOLINE DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1998-07-22 | — | — | EP | disclosed |
| WO-1997044342-A1 | PROCESS FOR PREPARING 1-ARYL-4-OXOPYRROLO[3,2-c]QUINOLINE DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1997-11-27 | — | — | WO | disclosed |