Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 18/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 17/20 | 0.41 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.38 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7892346 | 1.00 | HSP90AB1 (0.41) | HSP90AB1HSP90AA1HSP90B1TRAP1HDAC4 | |
| SCHEMBL8567029 | 1.00 | HSP90AB1 (0.41) | HSP90AB1HSP90AA1HSP90B1TRAP1HDAC4 | |
| SCHEMBL7892342 | 0.82 | HSP90AB1 (0.42) | HSP90AB1HSP90AA1HSP90B1TRAP1HDAC4 | |
| SCHEMBL7901451 | 0.82 | HSP90AB1 (0.42) | HSP90AB1HSP90AA1HSP90B1TRAP1HDAC4 | |
| SCHEMBL7898280 | 0.82 | HSP90AB1 (0.42) | HSP90AB1HSP90AA1HSP90B1TRAP1HDAC4 | |
| SCHEMBL7891828 | 0.81 | HSP90AB1 (0.43) | HSP90AB1HSP90AA1HSP90B1TRAP1HDAC4 | |
| SCHEMBL7892140 | 0.81 | HSP90AB1 (0.43) | HSP90AB1HSP90AA1HSP90B1TRAP1HDAC4 | |
| SCHEMBL7892176 | 0.78 | HSP90AB1 (0.46) | HSP90AB1HSP90AA1HSP90B1TRAP1 | |
| SCHEMBL7623763 | 0.78 | HSP90AB1 (0.46) | HSP90AB1HSP90AA1HSP90B1TRAP1 | |
| SCHEMBL7898274 | 0.78 | HSP90AB1 (0.46) | HSP90AB1HSP90AA1HSP90B1TRAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789394-A | VIRICIDES FOR CYTOMEGALOVIRUS USING NUCLEOTIDES | NGUYEN-BA NGHE (CA) | 1998-08-04 | — | — | US | claimed |