Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 19/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 18/20 | 0.46 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.42 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7623763 | 1.00 | HSP90AB1 (0.46) | HSP90AB1HSP90AA1HSP90B1TRAP1NT5E | |
| SCHEMBL7892176 | 1.00 | HSP90AB1 (0.46) | HSP90AB1HSP90AA1HSP90B1TRAP1NT5E | |
| SCHEMBL7892156 | 1.00 | HSP90AB1 (0.46) | HSP90AB1HSP90AA1HSP90B1TRAP1NT5E | |
| SCHEMBL7892344 | 1.00 | HSP90AB1 (0.46) | HSP90AB1HSP90AA1HSP90B1TRAP1NT5E | |
| SCHEMBL7892372 | 0.86 | FDPS (0.43) | — | |
| SCHEMBL7901477 | 0.86 | FDPS (0.43) | — | |
| SCHEMBL7898263 | 0.84 | HDAC6 (0.45) | HSP90AB1HSP90AA1HSP90B1TRAP1NT5E | |
| SCHEMBL7903265 | 0.84 | HDAC6 (0.45) | HSP90AB1HSP90AA1HSP90B1TRAP1NT5E | |
| SCHEMBL7619346 | 0.84 | HSP90AA1 (0.32) | HSP90AB1HSP90AA1NT5E | |
| SCHEMBL7892140 | 0.83 | HSP90AB1 (0.43) | HSP90AB1HSP90AA1HSP90B1TRAP1NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789394-A | VIRICIDES FOR CYTOMEGALOVIRUS USING NUCLEOTIDES | NGUYEN-BA NGHE (CA) | 1998-08-04 | — | — | US | claimed |
| US-6194576-B1 | COUPLING PURINE OR PYRIMIDINE BASE WITH NUCLEOTIDE ANALOG PHOSPHONATE COMPOUND | BIOCHEM PHARMA, INC. (CA) | 2001-02-27 | — | — | US | disclosed |
| US-6127540-A | NUCLEOTIDE ANALOGS MADE BY COUPLING A PURINE OR PYRIMIDINE NUCLEOTIDE BASE OR ANALOGUE THEREOF WITH A 2-(PHOSPHONATE)FURAN OR 2-(PHOSPHONATE)THIOFURAN OF GIVEN FORMULA; USE AS NON-TOXIC ANTIVIRAL DRUGS | BIOCHEM PHARMA, INC. (CA) | 2000-10-03 | — | — | US | disclosed |
| US-6005107-A | Antiviral compounds | BIOCHEM PHARMA, INC. (CA) | 1999-12-21 | — | — | US | disclosed |
| US-5955610-A | COUPLING PHOSPHONATE INTERMEDIATE WITH PURINE OR PYRIMIDINE NUCLEOTIDE BASE | BIOCHEM PHARMA, INC. (CA) | 1999-09-21 | — | — | US | disclosed |
| US-5789394-A | VIRICIDES FOR CYTOMEGALOVIRUS USING NUCLEOTIDES | NGUYEN-BA NGHE (CA) | 1998-08-04 | — | — | US | disclosed |