Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3573767 | 0.83 | L3MBTL1 (0.48) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL336115 | 0.79 | KMT2A (0.53) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL262196 | 0.79 | MEN1 (0.53) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL25457901 | 0.79 | FLT1 (0.38) | KMT2AALDH1A1RAB9ANPC1L3MBTL1 | |
| SCHEMBL16963334 | 0.78 | KMT2A (0.55) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL2660301 | 0.78 | MEN1 (0.51) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL29530824 | 0.77 | KMT2A (0.37) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL31460254 | 0.77 | MAPK1 (0.35) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL29158106 | 0.76 | KMT2A (0.50) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL31460107 | 0.76 | PIK3CD (0.37) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846990-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB CO. (US) | 1998-12-08 | — | — | US | claimed |