SCHEMBL8566918

SCHEMBL8566918

O=C(Oc1ccccc1)c1cccc([N+](=O)[O-])c1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 4/20 0.77
ALDH1A1 P00352 4/20 0.64
TP53 P04637 1/20 0.63
MAPT P10636 7/20 0.62
GAA P10253 2/20 0.62
TDP1 Q9NUW8 1/20 0.62
NPC1 O15118 1/20 0.61
RAB9A P51151 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
CES2 O00748 1/20 0.60
CES1 P23141 1/20 0.60
KDM4E B2RXH2 2/20 0.58
MEN1 O00255 1/20 0.57
POLB P06746 1/20 0.57
KMT2A Q03164 1/20 0.57
CTDSP1 Q9GZU7 1/20 0.57
TSHR P16473 2/20 0.57
HGFAC Q04756 1/20 0.56
F2 P00734 1/20 0.56
NPSR1 Q6W5P4 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9448725 0.92 ALOX5 (0.65) ALOX5ALDH1A1TP53MAPTGAA
SCHEMBL1546357 0.91 ALOX5 (0.68) ALOX5ALDH1A1TP53MAPTTDP1
SCHEMBL27935077 0.87 ALOX5 (1.00) ALOX5ALDH1A1MAPTGAATDP1
SCHEMBL24697326 0.85 MAPT (0.60) ALOX5ALDH1A1TP53MAPTGAA
SCHEMBL30686677 0.85 MAPT (0.60) ALOX5ALDH1A1TP53MAPTGAA
SCHEMBL13220849 0.84 MAPT (0.69) ALOX5ALDH1A1TP53MAPTGAA
SCHEMBL13292702 0.84 MAPT (0.67) ALOX5ALDH1A1MAPTGAATDP1
SCHEMBL4721016 0.84 TP53 (0.67) ALOX5ALDH1A1TP53MAPTGAA
SCHEMBL24696626 0.83 MAPT (0.61) ALOX5ALDH1A1TP53MAPTGAA
SCHEMBL9186944 0.82 HGFAC (0.62) ALOX5ALDH1A1TP53MAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10364300-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-07-30 US claimed
US-20170247478-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2017-08-31 US claimed
EP-3204429-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2017-08-16 EP claimed
WO-2016057388-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-04-14 WO claimed
EP-0345551-B1 EASILY FLOWABLE DELAYED CRYSTALLISING POLYARYLENE SULFIDE-MIXTURES BAYER AG (DE) 1993-09-08 EP claimed
CN-107567464-B Process for producing polydienes and polydiene copolymers having reduced cold flow properties 株式会社普利司通 2020-04-14 CN disclosed
US-10364300-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-07-30 US disclosed
EP-3204429-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2018-09-05 EP disclosed
US-9835961-B2 Phthalocyanine crystal, and electrophotographic photoreceptor, electrophotographic photoreceptor cartridge and image-forming device using the same MITSUBISHI CHEMICAL CORPORATION (JP) 2017-12-05 US disclosed
US-9835961-B2 Phthalocyanine crystal, and electrophotographic photoreceptor, electrophotographic photoreceptor cartridge and image-forming device using the same MITSUBISHI CHEMICAL CORPORATION (JP) 2017-12-05 US disclosed
US-20170336724-A1 PHTHALOCYANINE CRYSTAL, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE AND IMAGE-FORMING DEVICE USING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2017-11-23 US disclosed
US-20170336724-A1 PHTHALOCYANINE CRYSTAL, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE AND IMAGE-FORMING DEVICE USING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2017-11-23 US disclosed
US-20100232830-A1 PHTHALOCYANINE CRYSTAL, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE AND IMAGE-FORMING DEVICE USING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2010-09-16 US disclosed
WO-1998024776-A1 PREPARATION OF AN AMINOARYLAMINOARAZOLE THE DOW CHEMICAL COMPANY (US) 1998-06-11 WO disclosed
US-5739344-A Preparation of an aminoarylaminoarazole THE DOW CHEMICAL COMPANY (US) 1998-04-14 US disclosed
EP-0516849-B1 INDOLE DERIVATIVES FUJISAWA PHARMACEUTICAL CO (JP) 1995-01-25 EP disclosed
US-5283251-A Testosterone 5a-reductase inhibitors FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1994-02-01 US disclosed
EP-0516849-A1 INDOLE DERIVATIVES. FUJISAWA PHARMACEUTICAL CO (JP) 1992-12-09 EP disclosed
WO-1991013060-A1 INDOLE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1991-09-05 WO disclosed
US-4996256-A With aromatic mono-nitro compounds blended into melt; workability, molding materials BAYER AKTIENGESELLSCHAFT (DE) 1991-02-26 US disclosed