Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6221966 | 0.76 | DTYMK (0.50) | ALDH1A1MAPTHTTKMT2AGAA | |
| SCHEMBL21056719 | 0.76 | KDM4C (0.54) | ALDH1A1MAPTCYP1A2CYP2C9KMT2A | |
| SCHEMBL8568617 | 0.75 | MAPK1 (0.38) | ALDH1A1MAPTHTTKMT2AGAA | |
| SCHEMBL27546560 | 0.74 | KMT2A (0.49) | ALDH1A1MAPTHTTCYP1A2CYP2C9 | |
| SCHEMBL8561170 | 0.74 | MAPK1 (0.43) | ALDH1A1KMT2AKDM4ELMNACES2 | |
| SCHEMBL27855607 | 0.73 | KMT2A (0.71) | ALDH1A1MAPTHTTCYP1A2CYP2C9 | |
| SCHEMBL8561530 | 0.73 | HTT (0.52) | ALDH1A1MAPTHTTKMT2AGAA | |
| SCHEMBL8566546 | 0.72 | MEN1 (0.48) | ALDH1A1MAPTCYP1A2CYP2C9KMT2A | |
| SCHEMBL8561727 | 0.72 | KMT2A (0.42) | ALDH1A1MAPTHTTKMT2ASMN1; SMN2 | |
| SCHEMBL8560647 | 0.71 | HTT (0.50) | ALDH1A1MAPTHTTCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |