Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | BCL6 | P41182 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | PLAU | P00749 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8566551 | 0.77 | ALDH1A1 (0.46) | MAPK1POLBMEN1KMT2AHTT | |
| SCHEMBL8568707 | 0.75 | CES2 (0.39) | POLBHTTCES2CES1MAPT | |
| SCHEMBL8566992 | 0.75 | ALDH1A1 (0.47) | KMT2AHTTCES2MAPTALDH1A1 | |
| SCHEMBL8570524 | 0.74 | MAPT (0.42) | MAPK1POLBMEN1KMT2AHTT | |
| SCHEMBL8563757 | 0.73 | ALDH1A1 (0.40) | POLBMEN1KMT2AHTTMAPT | |
| SCHEMBL8569903 | 0.72 | MAPK1 (0.34) | MAPK1POLBMEN1KMT2AHTT | |
| SCHEMBL8565140 | 0.72 | HTT (0.55) | POLBMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL8565798 | 0.72 | RAB9A (0.55) | MAPK1POLBKMT2AMAPTALDH1A1 | |
| SCHEMBL8566844 | 0.72 | MEN1 (0.40) | POLBMEN1KMT2AHTTMAPT | |
| SCHEMBL30874786 | 0.72 | TDP1 (0.51) | MAPK1POLBMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |