SCHEMBL8567016

SCHEMBL8567016

O=Cc1cc(F)c(OCc2ccccc2)c(F)c1OCc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.45
MAOB P27338 4/20 0.45
ERN1 O75460 2/20 0.44
KDM1A O60341 5/20 0.44
CCNB2 O95067 1/20 0.42
CDK1 P06493 1/20 0.42
CDK4 P11802 1/20 0.42
CCNB1 P14635 1/20 0.42
CCND1 P24385 1/20 0.42
CCNB3 Q8WWL7 1/20 0.42
HPGD P15428 2/20 0.39
MAPT P10636 2/20 0.39
LMNA P02545 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
FFAR4 Q5NUL3 1/20 0.39
GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25367135 0.91 MAOA (0.45) MAOAMAOBERN1KDM1ACCNB2
SCHEMBL25367596 0.87 MAOA (0.42) MAOAMAOBERN1KDM1ACCNB2
SCHEMBL16033831 0.84 KDM1A (0.47) MAOAMAOBERN1KDM1ACCNB2
SCHEMBL21647646 0.84 KDM1A (0.43) MAOAMAOBERN1KDM1ACCNB2
SCHEMBL4055189 0.84 GAA (0.51) MAOAMAOBERN1KDM1ACCNB2
SCHEMBL28189420 0.82 ERN1 (0.49) MAOAMAOBERN1KDM1AHPGD
SCHEMBL2301807 0.81 MAOA (0.55) MAOAMAOBKDM1ACCNB2CDK1
SCHEMBL31056517 0.80 GAA (0.45) MAOAMAOBERN1CCNB2CDK1
SCHEMBL31114193 0.80 MAPT (0.48) MAOAMAOBERN1KDM1ACCNB2
SCHEMBL1163493 0.79 KDM1A (0.50) MAOAMAOBERN1KDM1ACCNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4676919-A1 MONOFLUORINATED COUMARIN FLUOROPHORES AND USES THEREOF Ohio State Innovation Foundation (US) 2026-01-14 EP disclosed
WO-2024186721-A1 MONOFLUORINATED COUMARIN FLUOROPHORES AND USES THEREOF OHIO STATE INNOVATION FOUNDATION (US) 2024-09-12 WO disclosed
US-5830912-A Derivatives of 6,8-difluoro-7-hydroxycoumarin MOLECULAR PROBES, INC. (US) 1998-11-03 US disclosed