Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8090461 | 0.99 | KDM4E (0.55) | KDM4EALDH1A1LMNA | |
| SCHEMBL8627194 | 0.93 | KDM4E (0.48) | KDM4EALDH1A1LMNA | |
| SCHEMBL8572297 | 0.88 | ACHE (0.48) | — | |
| SCHEMBL8090497 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL8087074 | 0.88 | GRIN1 (0.47) | — | |
| Bromide SCHEMBL8079006 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL8086855 | 0.87 | — | — | |
| SCHEMBL8569957 | 0.87 | — | — | |
| SCHEMBL8567318 | 0.87 | — | — | |
| SCHEMBL8565720 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853617-A1 | NOVEL 2,3-DIOXO-1,2,3,4-TETRAHYDRO-QUINOYXALINYL DERIVATIVES | Novartis AG (CH) | 1998-07-22 | — | — | EP | claimed |
| WO-1997008155-A1 | NOVEL 2,3-DIOXO-1,2,3,4-TETRAHYDRO-QUINOYXALINYL DERIVATIVES | NOVARTIS AG (CH) | 1997-03-06 | — | — | WO | claimed |