SCHEMBL8567074

SCHEMBL8567074

CC(=O)Nc1cnc(C(=O)O)c(C(=O)O)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.44
MYC P01106 1/20 0.44
KDM4E B2RXH2 6/20 0.43
HSD17B10 Q99714 3/20 0.41
NAPRT Q6XQN6 1/20 0.41
RORC P51449 1/20 0.41
LMNA P02545 1/20 0.40
PDE10A Q9Y233 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.39
OPRK1 P41145 1/20 0.38
MAPT P10636 3/20 0.38
ALDH1A1 P00352 3/20 0.38
TSHR P16473 2/20 0.38
CYP3A4 P08684 1/20 0.38
ALOX15 P16050 1/20 0.38
BLM P54132 1/20 0.38
AGER Q15109 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
EGLN1 Q9GZT9 1/20 0.38
MEN1 O00255 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7472653 0.82 KDM4E (0.49) KMT2AKDM4EL3MBTL1MAPTALDH1A1
SCHEMBL24387784 0.81 TDP1 (0.44) KMT2AKDM4EHSD17B10NAPRTRORC
SCHEMBL22288656 0.76 MALT1 (0.43) KMT2AMYCKDM4ERORCOPRK1
SCHEMBL9315419 0.73 KDM4E (0.41) KDM4EHSD17B10L3MBTL1MAPTALDH1A1
SCHEMBL8565045 0.72 TSHR (0.46) KMT2AKDM4ERORCLMNAMAPT
SCHEMBL30968742 0.72 GABRP (0.44) KMT2AKDM4EL3MBTL1MAPTALDH1A1
SCHEMBL1819716 0.72 GABRP (0.44) KMT2AKDM4EL3MBTL1MAPTALDH1A1
SCHEMBL28276724 0.71 GABRP (0.43) KMT2AKDM4EL3MBTL1MAPTALDH1A1
SCHEMBL2500845 0.71 MYC (0.61) KMT2AMYCKDM4EHSD17B10NAPRT
SCHEMBL22288600 0.70 SMN1; SMN2 (0.50) KMT2AKDM4EHSD17B10RORCLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0663399-B1 Pyridine-2,3-dicarboxylic imides, process for their preparation and their use to control the growth of unwanted plants BASF AG (DE) 1998-06-10 EP claimed
US-5334576-A Pre- and postemergence AMERICAN CYANAMID COMPANY (US) 1994-08-02 US disclosed
EP-0322616-A2 Novel 5(and/or 6)substituted 2-(2-imidazolin-2-yl)nicotinic acids, esters and salts, useful as herbicidal agents and nivel intermediates for the preparation of said nicotinic acids, esters and salts AMERICAN CYANAMID COMPANY (US) 1989-07-05 EP disclosed