SCHEMBL8567108

SCHEMBL8567108

C1=Nc2c3c(ncc2=C1)=CCS3

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31301154 0.69
SCHEMBL8121239 0.57
SCHEMBL6234127 0.48
SCHEMBL4507846 0.47 KDM4E (0.36)
SCHEMBL16878359 0.40
SCHEMBL6272478 0.39
SCHEMBL11489872 0.38
SCHEMBL2398838 0.38 CYP19A1 (0.30)
Ammonia Solution, Strong SCHEMBL27508580 0.32
SCHEMBL29846477 0.31 CDC25B (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260098044-A1 TRICYCLIC HETEROARYL COMPOUNDS AS INHIBITORS OF TYK2 AND/OR JAK1 INCYTE CORP (US) 2026-04-09 US disclosed
EP-0587473-B1 Condensed pyridine derivatives as inhibitors of the effects of free radicals SANOFI SA (FR) 1998-11-11 EP disclosed
US-5468750-A Antiinflammatory agents and autoimmune diseases ELF SANOFI (FR) 1995-11-21 US disclosed
US-5360799-A Free radical inhibitors ELF SANOFI (FR) 1994-11-01 US disclosed
EP-0587473-A1 Condensed pyridine derivatives as inhibitors of the effects of free radicals SANOFI (FR) 1994-03-16 EP disclosed