Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 3/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7450697 | 0.77 | TACR1 (0.49) | TACR1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL13625606 | 0.77 | CNR1 (0.50) | TACR1CNR1CNR2MEN1KMT2A | |
| SCHEMBL8414552 | 0.74 | KMT2A (0.46) | TACR1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL5883327 | 0.73 | TACR1 (0.54) | TACR1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL29469503 | 0.73 | TACR1 (0.49) | TACR1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL8684739 | 0.72 | TACR1 (0.51) | TACR1MEN1KMT2AALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL5883686 | 0.72 | TACR1 (0.52) | TACR1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL31393815 | 0.71 | TACR1 (0.51) | TACR1MEN1KMT2AALDH1A1KDM4E | |
| Diphenamide SCHEMBL402012 | 0.70 | KDM4E (0.50) | TACR1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL1551142 | 0.69 | CNR1 (0.56) | CNR1CNR2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846990-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB CO. (US) | 1998-12-08 | — | — | US | disclosed |