Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29469478 | 0.84 | KMT2A (0.52) | TACR1KDM4EALDH1A1GAAMEN1 | |
| SCHEMBL29469494 | 0.82 | KDM4C (0.49) | TACR1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL1046327 | 0.78 | ALDH1A1 (0.52) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL29469487 | 0.77 | TACR1 (0.44) | TACR1KDM4EALDH1A1GAAMEN1 | |
| SCHEMBL3930397 | 0.77 | TSPO (0.54) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL11315869 | 0.77 | ALDH1A1 (0.50) | KDM4EALDH1A1GAAGLAHPGD | |
| Diphenamide SCHEMBL11702462 | 0.76 | TACR1 (0.48) | TACR1KDM4EALDH1A1MEN1KMT2A | |
| Diphenamide SCHEMBL15619425 | 0.75 | ALDH1A1 (0.58) | TACR1KDM4EALDH1A1GAAHPGD | |
| SCHEMBL4276628 | 0.75 | ALDH1A1 (0.49) | KDM4EALDH1A1GAAGLAHPGD | |
| Diphenamide SCHEMBL40535 | 0.74 | KDM4E (0.48) | TACR1KDM4EALDH1A1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206443-B | Aromatic or heteroaromatic ring derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-114206443-A | Aromatic ring or heteroaromatic ring derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2022-03-18 | — | — | CN | disclosed |