Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.55 |
| ▸ | MGAM | O43451 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | SI | P14410 | 2/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | MPL | P40238 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5692672 | 0.87 | PDPK1 (0.64) | PDPK1RAB9AALDH1A1CYP2A6ADRA1A | |
| SCHEMBL1951149 | 0.85 | PDPK1 (0.61) | PDPK1RAB9AALDH1A1CYP2A6ADRA1A | |
| SCHEMBL16681431 | 0.79 | KDM4E (0.43) | PDPK1RAB9AKDM4EALDH1A1CYP2A6 | |
| SCHEMBL28020115 | 0.79 | PDPK1 (0.50) | PDPK1MGAMGAASIMGAM2 | |
| SCHEMBL5912405 | 0.79 | F2RL1 (0.51) | PDPK1MGAMGAASIMGAM2 | |
| SCHEMBL26259375 | 0.78 | PDPK1 (0.59) | PDPK1GAARAB9AKDM4EALDH1A1 | |
| SCHEMBL26259560 | 0.78 | PDPK1 (0.54) | PDPK1RAB9ACYP2A6ADRA1AADRA1D | |
| SCHEMBL29014181 | 0.78 | HCRTR1 (0.51) | PDPK1MGAMGAASIMGAM2 | |
| SCHEMBL2175845 | 0.78 | PDPK1 (0.70) | PDPK1RAB9ACYP2A6ADRA1AADRA1D | |
| SCHEMBL5327036 | 0.78 | PDPK1 (0.53) | PDPK1RAB9AALDH1A1CYP2A6ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110437173-A | A kind of diphenylethylene compounds and its synthetic method and application containing thiazole ring | UNIV ZHEJIANG TECHNOLOGY | 2019-11-12 | — | — | CN | disclosed |
| CN-107531660-A | α cinnamide compounds and composition as HDAC8 inhibitor | 福马治疗股份有限公司 | 2018-01-02 | — | — | CN | disclosed |
| CN-104059060-B | A kind of ketones derivant of 5 (methylene of 1H indoles 3) 1,3 thiazolidine 4 and its synthetic method and application | 西安交通大学 | 2017-08-01 | — | — | CN | disclosed |
| CN-103209695-A | Azabenzothiazole compounds, compositions and methods of use | HOFFMANN LA ROCHE | 2013-07-17 | — | — | CN | disclosed |
| WO-1998000756-A1 | SILVER HALIDE EMULSIONS | POLAROID CORPORATION (US) | 1998-01-08 | — | — | WO | disclosed |