Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | RARB | P10826 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | ATP4A | P20648 | 2/20 | 0.39 |
| ▸ | ATP4B | P51164 | 2/20 | 0.39 |
| ▸ | MLNR | O43193 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8572192 | 0.94 | LTA4H (0.43) | SOAT1LTA4HPTPN1ATP4AATP4B | |
| SCHEMBL15503241 | 0.78 | RARB (0.50) | LTA4HRARBTSHRATP4AATP4B | |
| SCHEMBL9453080 | 0.76 | NR5A1 (0.39) | LTA4HTSHRESR1 | |
| SCHEMBL10414226 | 0.76 | NR5A1 (0.39) | LTA4HTSHRESR1 | |
| SCHEMBL30179464 | 0.74 | CYP11B1 (0.42) | RARBCNR2CNR1KCNH2 | |
| SCHEMBL21391973 | 0.74 | CYP11B1 (0.42) | RARBCNR2CNR1KCNH2 | |
| Biphenyl SCHEMBL2989570 | 0.74 | LTA4H (0.50) | SOAT1LTA4HPTPN1RARBTSHR | |
| Biphenyl SCHEMBL15361572 | 0.74 | LTA4H (0.50) | SOAT1LTA4HPTPN1RARBTSHR | |
| Biphenyl SCHEMBL7863473 | 0.74 | LTA4H (0.50) | SOAT1LTA4HPTPN1RARBTSHR | |
| Biphenyl SCHEMBL2991687 | 0.74 | LTA4H (0.50) | SOAT1LTA4HPTPN1RARBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843951-A | Analgesic composition of pyrazolo(1,5-A) pyrimidines | OTSUKA PHARMACEUTICAL FACTORY INC. (JP) | 1998-12-01 | — | — | US | disclosed |
| EP-0795555-A1 | ANALGESICS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1997-09-17 | — | — | EP | disclosed |