SCHEMBL8567419

SCHEMBL8567419

O=C1CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC(=O)N1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 6/20 0.80
FKBP5 Q13451 1/20 0.50
ALDH1A1 P00352 3/20 0.47
TRIM24 O15164 2/20 0.47
TRIM33 Q9UPN9 2/20 0.47
OR51E2 Q9H255 1/20 0.45
MAPT P10636 3/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
RAB9A P51151 2/20 0.40
CYP2C19 P33261 2/20 0.40
TSHR P16473 1/20 0.40
HPGD P15428 2/20 0.37
HTT P42858 1/20 0.37
ALOX15 P16050 1/20 0.34
ALOX12 P18054 1/20 0.34
BLM P54132 1/20 0.34
HSD17B10 Q99714 1/20 0.34
MAPK1 P28482 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2912717 1.00 CRBN (0.80) CRBNFKBP5ALDH1A1TRIM24TRIM33
SCHEMBL6049487 1.00 CRBN (0.80) CRBNFKBP5ALDH1A1TRIM24TRIM33
SCHEMBL18301008 1.00 CRBN (0.80) CRBNFKBP5ALDH1A1TRIM24TRIM33
SCHEMBL9716416 1.00 CRBN (0.80) CRBNFKBP5ALDH1A1TRIM24TRIM33
SCHEMBL19350697 1.00 CRBN (0.80) CRBNFKBP5ALDH1A1TRIM24TRIM33
SCHEMBL23028960 1.00 CRBN (0.80) CRBNFKBP5ALDH1A1TRIM24TRIM33
SCHEMBL8801853 1.00 CRBN (0.80) CRBNFKBP5ALDH1A1TRIM24TRIM33
SCHEMBL5909153 1.00 CRBN (0.80) CRBNFKBP5ALDH1A1TRIM24TRIM33
SCHEMBL1335950 0.96
SCHEMBL7888543 0.93 CRBN (0.80) CRBNFKBP5ALDH1A1TRIM24TRIM33

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0684261-B1 Emulsion polymerisation inhibitor and suspension polymerisation method using the agent NIPPON CATALYTIC CHEM IND (JP) 1999-08-11 EP disclosed
US-5605992-A HOMO OR COPOLYMERIZING MONOMERS SELECTED FROM STYRENE AND ACRYLIC IN PRESENCE OF AN AROMATIC SERIES COMPOUND WHICH HAS NITRO, SECONDARY AMINO, AND SODIUM SULFONATE GROUPS NIPPON SHOKUBAI CO., LTD. (JP) 1997-02-25 US disclosed
EP-0684261-A2 Emulsion polymerisation inhibitor and suspension polymerisation method using the agent NIPPON SHOKUBAI CO., LTD. (JP) 1995-11-29 EP disclosed