Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.67 |
| ▸ | RAB9A | P51151 | 10/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.60 |
| ▸ | GAA | P10253 | 5/20 | 0.60 |
| ▸ | PKM | P14618 | 4/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25243870 | 0.82 | KCNH2 (0.57) | NPC1RAB9ASMN1; SMN2GAAMAPT | |
| SCHEMBL25788813 | 0.82 | RAB9A (0.58) | NPC1RAB9ASMN1; SMN2GAAPKM | |
| SCHEMBL25245167 | 0.82 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2GAAPKM | |
| SCHEMBL15022003 | 0.82 | RAB9A (0.78) | NPC1RAB9ASMN1; SMN2GAAPKM | |
| SCHEMBL22285903 | 0.80 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2GAAPKM | |
| SCHEMBL1853314 | 0.80 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2GAAPKM | |
| SCHEMBL3957488 | 0.80 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2GAAPKM | |
| SCHEMBL29972698 | 0.77 | NPC1 (0.75) | NPC1RAB9ASMN1; SMN2GAAPKM | |
| SCHEMBL27886383 | 0.77 | RAB9A (0.65) | NPC1RAB9ASMN1; SMN2GAAPKM | |
| SCHEMBL1699100 | 0.77 | NPC1 (0.75) | NPC1RAB9ASMN1; SMN2GAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998024776-A1 | PREPARATION OF AN AMINOARYLAMINOARAZOLE | THE DOW CHEMICAL COMPANY (US) | 1998-06-11 | — | — | WO | disclosed |
| US-5739344-A | Preparation of an aminoarylaminoarazole | THE DOW CHEMICAL COMPANY (US) | 1998-04-14 | — | — | US | disclosed |