Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 3/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567655 | 1.00 | MEN1 (0.40) | MEN1KMT2AUSP2KEAP1NFE2L2 | |
| SCHEMBL8565832 | 0.80 | TAAR1 (0.50) | MEN1KMT2ANFE2L2MAPTALDH1A1 | |
| SCHEMBL8561311 | 0.78 | MEN1 (0.35) | MEN1KMT2AUSP2KEAP1NFE2L2 | |
| SCHEMBL8561307 | 0.78 | MEN1 (0.35) | MEN1KMT2AUSP2KEAP1NFE2L2 | |
| SCHEMBL8566303 | 0.74 | MAPT (0.40) | MEN1KMT2AUSP2KEAP1NFE2L2 | |
| SCHEMBL8566306 | 0.74 | MAPT (0.40) | MEN1KMT2AUSP2KEAP1NFE2L2 | |
| SCHEMBL203785 | 0.74 | MEN1 (0.41) | MEN1KMT2AUSP2KEAP1NFE2L2 | |
| SCHEMBL30622636 | 0.74 | MEN1 (0.41) | MEN1KMT2AUSP2KEAP1NFE2L2 | |
| SCHEMBL3688848 | 0.73 | MAPT (0.47) | MEN1KMT2AUSP2KEAP1NFE2L2 | |
| SCHEMBL18486948 | 0.72 | KMT2A (0.42) | MEN1KMT2AUSP2KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |