Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 6/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567654 | 0.80 | MEN1 (0.40) | NFE2L2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL8567655 | 0.80 | MEN1 (0.40) | NFE2L2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL8570526 | 0.77 | TAAR1 (0.43) | TAAR1NFE2L2MAPTMEN1KMT2A | |
| SCHEMBL8561311 | 0.74 | MEN1 (0.35) | NFE2L2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL8561307 | 0.74 | MEN1 (0.35) | NFE2L2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL1736679 | 0.74 | TAAR1 (0.57) | TAAR1NFE2L2MAPTMEN1KMT2A | |
| SCHEMBL1736681 | 0.74 | TAAR1 (0.57) | TAAR1NFE2L2MAPTMEN1KMT2A | |
| SCHEMBL8855377 | 0.74 | NFE2L2 (0.50) | TAAR1NFE2L2MAPTMEN1KMT2A | |
| SCHEMBL8560906 | 0.72 | TAAR1 (0.46) | TAAR1NFE2L2MAPTMEN1KMT2A | |
| SCHEMBL8662385 | 0.72 | ABCC8 (0.43) | NFE2L2MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |