Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567660 | 1.00 | ATM (0.58) | ATMMEN1KMT2AALDH1A1POLB | |
| SCHEMBL19327293 | 0.83 | ATM (0.63) | ATMMEN1KMT2AALDH1A1POLB | |
| SCHEMBL12017418 | 0.83 | ATM (0.63) | ATMMEN1KMT2AALDH1A1POLB | |
| SCHEMBL19858919 | 0.81 | ATM (0.58) | ATMMEN1KMT2AALDH1A1POLB | |
| SCHEMBL6894880 | 0.81 | ATM (0.54) | ATMMEN1KMT2AALDH1A1POLB | |
| SCHEMBL19327311 | 0.79 | ATM (0.56) | ATMMEN1KMT2AALDH1A1POLB | |
| SCHEMBL892661 | 0.78 | ATM (0.54) | ATMMEN1KMT2AALDH1A1POLB | |
| SCHEMBL17324572 | 0.78 | ATM (0.54) | ATMMEN1KMT2AALDH1A1POLB | |
| SCHEMBL28437828 | 0.78 | HDAC1 (0.48) | ALDH1A1MGLLDRD2HTR6ADRB1 | |
| SCHEMBL8560583 | 0.78 | KMT2A (0.53) | MEN1KMT2AALDH1A1POLBMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804577-A | ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1998-09-08 | — | — | US | disclosed |
| EP-0761673-A1 | Cephalosporin derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1997-03-12 | — | — | EP | disclosed |