Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.70 |
| ▸ | TERT | O14746 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | BACE1 | P56817 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.53 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.53 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.53 |
| ▸ | PIM1 | P11309 | 1/20 | 0.53 |
| ▸ | TOP2A | P11388 | 1/20 | 0.53 |
| ▸ | CASR | P41180 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17749563 | 0.92 | TSHR (0.86) | TSHRKDM4EGAAHSD17B10TERT | |
| SCHEMBL8567589 | 0.88 | TSHR (0.78) | TSHRKDM4EGAAHSD17B10RAB9A | |
| SCHEMBL7521873 | 0.85 | TSHR (0.73) | TSHRKDM4EGAAHSD17B10RAB9A | |
| Bromide SCHEMBL7520808 | 0.84 | TSHR (0.72) | TSHRKDM4EGAAHSD17B10RAB9A | |
| SCHEMBL14325669 | 0.83 | TSHR (0.70) | TSHRKDM4EGAAHSD17B10TERT | |
| SCHEMBL14247437 | 0.83 | TSHR (0.70) | TSHRKDM4EGAAHSD17B10TERT | |
| SCHEMBL2445746 | 0.82 | BACE1 (0.73) | TSHRKDM4EGAAHSD17B10RAB9A | |
| SCHEMBL8250141 | 0.82 | TSHR (0.69) | TSHRKDM4EGAAHSD17B10TERT | |
| SCHEMBL2446553 | 0.79 | BACE1 (0.69) | TSHRRAB9ATP53BACE1HTT | |
| SCHEMBL7519030 | 0.78 | DRD4 (0.67) | TSHRKDM4ERAB9ABACE1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571253-B1 | Benzimidazole derivatives with antidiabetic and antiplatelet aggregation activity | ADIR (FR) | 1998-11-04 | — | — | EP | disclosed |
| US-5639756-A | ANTIDIABETIC AGENTS | ADIR ET COMPAGNIE (FR) | 1997-06-17 | — | — | US | disclosed |
| US-5623073-A | ANTIDIABETIC AGENT | ADIR ET COMPAGNIE (FR) | 1997-04-22 | — | — | US | disclosed |
| EP-0571253-A1 | Benzimidazole derivatives with antidiabetic and antiplatelet aggregation activity | ADIR ET COMPAGNIE (FR) | 1993-11-24 | — | — | EP | disclosed |