Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 6/20 | 0.35 |
| ▸ | CES1 | P23141 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18092559 | 0.82 | CES2 (0.35) | CES2CES1FFAR3HDAC3HDAC1 | |
| SCHEMBL2729247 | 0.82 | CES2 (0.35) | CES2CES1FFAR3HDAC3HDAC1 | |
| SCHEMBL1787331 | 0.82 | CES2 (0.35) | TSHRCES2CES1FFAR3HDAC3 | |
| SCHEMBL16536152 | 0.82 | CES2 (0.35) | CES2CES1FFAR3HDAC3HDAC1 | |
| SCHEMBL15643453 | 0.80 | — | — | |
| SCHEMBL1976924 | 0.80 | TSHR (0.33) | TSHRTHRBCES2CES1 | |
| SCHEMBL6449559 | 0.80 | TSHR (0.33) | TSHRTHRBCES2CES1 | |
| SCHEMBL3658482 | 0.80 | TSHR (0.33) | TSHRTHRBCES2CES1 | |
| SCHEMBL3458910 | 0.80 | — | — | |
| SCHEMBL6448290 | 0.80 | TSHR (0.33) | TSHRTHRBCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0652918-B1 | ABRASIVE GRAIN WITH METAL OXIDE COATING, METHOD OF MAKING SAME AND ABRASIVE PRODUCTS | MINNESOTA MINING & MFG (US) | 1998-10-21 | — | — | EP | disclosed |
| US-5474583-A | Alumina core with coating from hydrolyzing metal alkoxide to hydroxide, then sintering | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-12-12 | — | — | US | disclosed |
| EP-0652918-A1 | ABRASIVE GRAIN WITH METAL OXIDE COATING, METHOD OF MAKING SAME AND ABRASIVE PRODUCTS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-05-17 | — | — | EP | disclosed |
| WO-1994002560-A1 | ABRASIVE GRAIN WITH METAL OXIDE COATING, METHOD OF MAKING SAME AND ABRASIVE PRODUCTS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-02-03 | — | — | WO | disclosed |