Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.57 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.57 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | IDH1 | O75874 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12646452 | 0.86 | HCAR2 (0.56) | HCAR2HRH3FFAR1HSD17B1HSD17B2 | |
| SCHEMBL2772418 | 0.85 | CYP4F2 (0.68) | CYP4F2CYP4A11HRH3FFAR1CYP4Z1 | |
| SCHEMBL435053 | 0.85 | CYP4F2 (0.68) | CYP4F2CYP4A11HRH3CYP4Z1SYK | |
| SCHEMBL2745464 | 0.84 | CYP4F2 (0.57) | CYP4F2CYP4A11 | |
| SCHEMBL2083064 | 0.83 | CYP4F2 (0.54) | CYP4F2CYP4A11HRH3FFAR1CYP4Z1 | |
| SCHEMBL18670035 | 0.82 | CYP4F2 (0.48) | CYP4F2CYP4A11HCAR2HSD17B1HSD17B2 | |
| SCHEMBL30540945 | 0.82 | FFAR1 (0.55) | CYP4F2CYP4A11HRH3FFAR1SYK | |
| SCHEMBL2083299 | 0.82 | CYP4F2 (0.52) | CYP4F2CYP4A11HRH3FFAR1CYP4Z1 | |
| SCHEMBL8903063 | 0.81 | TDP1 (0.56) | CYP4F2CYP4A11FFAR1SYKAKR1B1 | |
| SCHEMBL13678667 | 0.81 | CYP4F2 (0.55) | CYP4F2CYP4A11FFAR1CYP4Z1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112457280-B | Synthesis of terphenyl compounds | 维克图斯生物系统有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-112457280-A | Synthesis of terphenyl compounds | 维克图斯生物系统有限公司 | 2021-03-09 | — | — | CN | disclosed |
| CN-108349872-B | Synthesis of terphenyl compounds | 维克图斯生物系统有限公司 | 2020-12-18 | — | — | CN | disclosed |
| EP-0544488-B1 | Substituted phenyl phenol leukotriene antagonists | LILLY CO ELI (US) | 1998-03-11 | — | — | EP | disclosed |
| CN-1035001-C | Substituted phenyl phenol leukotriene antagonists | LILLY CO ELI (US) | 1997-05-28 | — | — | CN | disclosed |
| EP-0743064-A1 | Leukotriene antagonists for use in the treatment or prevention of alzheimer's disease | ELI LILLY AND COMPANY (US) | 1996-11-20 | — | — | EP | disclosed |
| US-5462954-A | Antiinflammatory, antiallergens; treating asthma | ELI LILLY AND COMPANY (US) | 1995-10-31 | — | — | US | disclosed |
| CN-1088906-A | The phenyl phenol leukotriene antagonists that replaces | LILLY CO ELI (US) | 1994-07-06 | — | — | CN | disclosed |
| EP-0544488-A2 | Substituted phenyl phenol leukotriene antagonists | ELI LILLY AND COMPANY (US) | 1993-06-02 | — | — | EP | disclosed |