Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.48 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26683190 | 0.88 | CYP4F2 (0.56) | CYP4F2CYP4A11PTGER4PTGER3PTGER1 | |
| SCHEMBL18670104 | 0.83 | PTGER4 (0.67) | PTGER4PTGER3PTGER1PTGER2ALDH1A1 | |
| SCHEMBL2536319 | 0.82 | CYP4F2 (0.55) | CYP4F2CYP4A11PTGER4PTGER3PTGER1 | |
| SCHEMBL8567926 | 0.82 | CYP4F2 (0.57) | CYP4F2CYP4A11NPC1RAB9AHCAR2 | |
| SCHEMBL22886267 | 0.82 | ALDH1A1 (0.40) | CYP4F2CYP4A11PTGER4PTGER3PTGER1 | |
| SCHEMBL38660533 | 0.82 | CYP4F2 (0.50) | CYP4F2CYP4A11PTPN1ALDH1A1GAA | |
| SCHEMBL18075750 | 0.82 | CYP4F2 (0.41) | CYP4F2CYP4A11PTPN1ALDH1A1GAA | |
| SCHEMBL1810558 | 0.82 | CYP4F2 (0.50) | CYP4F2CYP4A11PTPN1ALDH1A1GAA | |
| SCHEMBL16589206 | 0.81 | PTGER4 (0.52) | PTGER4PTGER3PTGER1PTGER2NPC1 | |
| SCHEMBL38661151 | 0.81 | CYP4F2 (0.41) | CYP4F2CYP4A11PTPN1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11401235-B2 | Synthesis of terphenyl compounds | VECTUS BIOSYSTEMS LIMITED (AU) | 2022-08-02 | — | — | US | disclosed |
| EP-3353147-B1 | SYNTHESIS OF TERPHENYL COMPOUNDS | VECTUS BIOSYSTEMS LTD (AU) | 2021-01-13 | — | — | EP | disclosed |
| EP-3353147-B1 | SYNTHESIS OF TERPHENYL COMPOUNDS | VECTUS BIOSYSTEMS LTD (AU) | 2021-01-13 | — | — | EP | disclosed |
| US-20200399202-A1 | SYNTHESIS OF TERPHENYL COMPOUNDS | BORON MOLECULAR PTY LTD (AU) | 2020-12-24 | — | — | US | disclosed |
| US-20200399202-A1 | SYNTHESIS OF TERPHENYL COMPOUNDS | BORON MOLECULAR PTY LTD (AU) | 2020-12-24 | — | — | US | disclosed |
| US-10752578-B2 | Synthesis of terphenyl compounds | VECTUS BIOSYSTEMS LIMITED (AU) | 2020-08-25 | — | — | US | disclosed |
| US-10752578-B2 | Synthesis of terphenyl compounds | VECTUS BIOSYSTEMS LIMITED (AU) | 2020-08-25 | — | — | US | disclosed |
| US-20180282261-A1 | SYNTHESIS OF TERPHENYL COMPOUNDS | BORON MOLECULAR PTY LTD (AU) | 2018-10-04 | — | — | US | disclosed |
| EP-3353147-A1 | SYNTHESIS OF TERPHENYL COMPOUNDS | Vectus Biosystems Limited (AU) | 2018-08-01 | — | — | EP | disclosed |
| CN-108349872-A | Synthesis of terphenyl compounds | 维克图斯生物系统有限公司 | 2018-07-31 | — | — | CN | disclosed |
| WO-2017049343-A1 | SYNTHESIS OF TERPHENYL COMPOUNDS | VECTUS BIOSYSTEMS LIMITED (AU) | 2017-03-30 | — | — | WO | disclosed |
| WO-2017049343-A1 | SYNTHESIS OF TERPHENYL COMPOUNDS | VECTUS BIOSYSTEMS LIMITED (AU) | 2017-03-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11401235-B2 | Synthesis of terphenyl compounds | FDPS, TBXAS1, DHPS | CYP4F2 18/4885CYP4A11 40/4885PTGER4 851/4885 |
| US-20200399202-A1 | SYNTHESIS OF TERPHENYL COMPOUNDS | FDPS, TBXAS1, DHPS | CYP4F2 18/4885CYP4A11 40/4885PTGER4 851/4885 |
| US-20180282261-A1 | SYNTHESIS OF TERPHENYL COMPOUNDS | FDPS, TBXAS1, DHPS | CYP4F2 18/4885CYP4A11 40/4885PTGER4 851/4885 |
| US-10752578-B2 | Synthesis of terphenyl compounds | FDPS, TBXAS1, DHPS | CYP4F2 18/4885CYP4A11 40/4885PTGER4 851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.