Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.73 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5815673 | 0.86 | L3MBTL1 (0.71) | L3MBTL1MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL28915977 | 0.83 | L3MBTL1 (0.68) | L3MBTL1MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL12903055 | 0.83 | MEN1 (0.73) | L3MBTL1MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL29727186 | 0.83 | L3MBTL1 (0.67) | L3MBTL1MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL29727188 | 0.83 | L3MBTL1 (0.67) | L3MBTL1MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL1305492 | 0.83 | L3MBTL1 (0.67) | L3MBTL1MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL31435202 | 0.83 | HTT (0.71) | L3MBTL1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL28234816 | 0.82 | L3MBTL1 (0.61) | L3MBTL1MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL30978278 | 0.81 | L3MBTL1 (0.69) | L3MBTL1MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL13209744 | 0.81 | L3MBTL1 (0.69) | L3MBTL1MEN1KMT2ASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846990-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB CO. (US) | 1998-12-08 | — | — | US | claimed |