Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 19/20 | 0.78 |
| ▸ | FPR1 | P21462 | 1/20 | 0.74 |
| ▸ | FPR3 | P25089 | 8/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL727350 | 1.00 | FPR2 (0.78) | FPR2FPR1FPR3 | |
| SCHEMBL2683245 | 1.00 | FPR2 (0.78) | FPR2FPR1FPR3 | |
| SCHEMBL9985206 | 0.89 | FPR2 (0.75) | FPR2FPR1FPR3 | |
| SCHEMBL728813 | 0.89 | FPR2 (0.75) | FPR2FPR1FPR3 | |
| SCHEMBL728574 | 0.88 | FPR2 (0.73) | FPR2FPR1FPR3 | |
| SCHEMBL854989 | 0.88 | FPR2 (1.00) | FPR2FPR1FPR3 | |
| SCHEMBL728485 | 0.88 | FPR2 (1.00) | FPR2FPR1FPR3 | |
| SCHEMBL2684413 | 0.88 | FPR2 (1.00) | FPR2FPR1FPR3 | |
| SCHEMBL724717 | 0.87 | FPR2 (1.00) | FPR2FPR1FPR3 | |
| SCHEMBL9985273 | 0.87 | FPR2 (1.00) | FPR2FPR1FPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432760-A1 | BRIDGED SPIRO [2.4]HEPTANE DERIVATIVES AS ALX RECEPTOR AND/OR FPRL2 AGONISTS | Actelion Pharmaceuticals Ltd. (CH) | 2012-03-28 | — | — | EP | disclosed |