Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 7/20 | 0.56 |
| ▸ | IKBKB | O14920 | 4/20 | 0.56 |
| ▸ | RARG | P13631 | 9/20 | 0.40 |
| ▸ | RARB | P10826 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.40 |
| ▸ | GOT1 | P17174 | 1/20 | 0.40 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8394298 | 0.93 | RARA (0.50) | RARAIKBKBRARGRARBMEN1 | |
| SCHEMBL8570420 | 0.90 | RARA (0.45) | RARAIKBKBRARGRARBMEN1 | |
| SCHEMBL8566497 | 0.89 | RARA (0.50) | RARAIKBKBRARGRARBMEN1 | |
| SCHEMBL8567725 | 0.86 | RARA (0.52) | RARAIKBKBRARGRARBMEN1 | |
| SCHEMBL8570423 | 0.86 | RARA (0.59) | RARAIKBKBRARGRARBMEN1 | |
| SCHEMBL8568876 | 0.85 | RARA (0.41) | RARAIKBKBRARGRARBMEN1 | |
| SCHEMBL8690305 | 0.85 | IKBKB (0.54) | RARAIKBKBRARGRARBMEN1 | |
| SCHEMBL8690758 | 0.85 | RARA (0.65) | RARAIKBKBRARGRARBMEN1 | |
| SCHEMBL8617716 | 0.85 | RARA (0.70) | RARAIKBKBRARGRARBMEN1 | |
| SCHEMBL8570955 | 0.85 | RARA (0.40) | RARAIKBKBRARGRARBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5798354-A | COSMETIC, THERAPY | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-08-25 | — | — | US | claimed |
| US-5827500-A | TOPICAL SKIN TESTING THE ANIMAL RESPONSES BY APPLYING RETINOIC ACID RECEPTOR AGONIST AND ANTAGONIST | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-10-27 | — | — | US | disclosed |
| US-5798354-A | COSMETIC, THERAPY | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-08-25 | — | — | US | disclosed |