Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 3/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.54 |
| ▸ | TACR1 | P25103 | 3/20 | 0.52 |
| ▸ | TACR2 | P21452 | 2/20 | 0.52 |
| ▸ | CIB1 | Q99828 | 2/20 | 0.51 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.50 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30179434 | 0.87 | OXTR (0.68) | OXTRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL31332253 | 0.86 | HDAC3 (0.58) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Bq-123 SCHEMBL29388467 | 0.84 | PDCD1 (0.60) | OXTRHDAC3HDAC4HDAC1HDAC7 | |
| Bq-123 SCHEMBL11916897 | 0.84 | PDCD1 (0.60) | OXTRHDAC3HDAC4HDAC1HDAC7 | |
| Bq-123 SCHEMBL1290617 | 0.84 | PDCD1 (0.60) | OXTRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL16431734 | 0.82 | HDAC3 (0.55) | OXTRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29553179 | 0.81 | TACR1 (0.61) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL24614245 | 0.81 | HDAC3 (0.72) | OXTRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL30833606 | 0.81 | HDAC3 (0.72) | OXTRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL19605615 | 0.81 | HDAC3 (0.71) | OXTRHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5801222-A | Isolation and structure of the human cancer cell growth inhibitory cyclic octapeptides phakellistatin 10 and 11 | ARIZONA BOARD OF REGENTS ACTING ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 1998-09-01 | — | — | US | claimed |
| US-5801222-A | Isolation and structure of the human cancer cell growth inhibitory cyclic octapeptides phakellistatin 10 and 11 | ARIZONA BOARD OF REGENTS ACTING ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 1998-09-01 | — | — | US | disclosed |
| US-5801222-A | Isolation and structure of the human cancer cell growth inhibitory cyclic octapeptides phakellistatin 10 and 11 | ARIZONA BOARD OF REGENTS ACTING ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 1998-09-01 | — | — | US | disclosed |
| US-5801222-A | Isolation and structure of the human cancer cell growth inhibitory cyclic octapeptides phakellistatin 10 and 11 | ARIZONA BOARD OF REGENTS ACTING ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 1998-09-01 | — | — | US | disclosed |