Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | EGFR | P00533 | 2/20 | 0.55 |
| ▸ | SRC | P12931 | 1/20 | 0.55 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.44 |
| ▸ | GPR3 | P46089 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17484805 | 0.81 | TSHR (0.66) | TSHRKDM4EL3MBTL1EGFRSRC | |
| SCHEMBL30639179 | 0.81 | KDM4E (0.67) | TSHRKDM4EL3MBTL1EGFRALDH1A1 | |
| SCHEMBL1092586 | 0.81 | KDM4E (0.67) | TSHRKDM4EL3MBTL1EGFRALDH1A1 | |
| SCHEMBL4208219 | 0.80 | KDM4E (0.62) | TSHRKDM4EL3MBTL1EGFRSRC | |
| SCHEMBL9987688 | 0.80 | TSHR (0.42) | TSHRKDM4EL3MBTL1EGFRSRC | |
| SCHEMBL35212204 | 0.79 | TSHR (0.64) | TSHRKDM4EL3MBTL1EGFRSRC | |
| SCHEMBL9959978 | 0.79 | TSHR (0.64) | TSHRKDM4EL3MBTL1EGFRSRC | |
| SCHEMBL6595214 | 0.79 | TSHR (0.64) | TSHRKDM4EL3MBTL1EGFRSRC | |
| Potassium Ion SCHEMBL11790616 | 0.79 | TSHR (0.64) | TSHRKDM4EL3MBTL1EGFRSRC | |
| SCHEMBL25433493 | 0.78 | TSHR (0.51) | TSHRKDM4EALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846990-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB CO. (US) | 1998-12-08 | — | — | US | claimed |