Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | GSK3A | P49840 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8568623 | 1.00 | GAA (0.52) | GAAGSK3AGSK3BALDH1A1MAPT | |
| SCHEMBL7575421 | 0.90 | GRIN2D (0.50) | GSK3AGSK3BALDH1A1MAPTKDM4E | |
| SCHEMBL7575423 | 0.90 | GRIN2D (0.50) | GSK3AGSK3BALDH1A1MAPTKDM4E | |
| SCHEMBL7573981 | 0.83 | GRIN2D (0.47) | GSK3BALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL7573978 | 0.83 | GRIN2D (0.47) | GSK3BALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL4231715 | 0.76 | GAA (0.59) | GAAALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL20871099 | 0.76 | GAA (0.59) | GAAALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL4231718 | 0.76 | GAA (0.59) | GAAALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL7580330 | 0.75 | ALDH1A1 (0.51) | GAAALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL3674337 | 0.73 | MAPT (0.64) | GAAALDH1A1MAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756769-A | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1998-05-26 | — | — | US | disclosed |