Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8568653 | 1.00 | MMP8 (0.51) | MMP8KMT2AMMEL3MBTL1GAA | |
| SCHEMBL8514567 | 0.86 | KMT2A (0.53) | MMP8KMT2AMMEGAAALDH1A1 | |
| SCHEMBL27520455 | 0.86 | KMT2A (0.53) | KMT2AALDH1A1MEN1 | |
| SCHEMBL10638067 | 0.85 | KMT2A (0.53) | MMP8KMT2AMMEL3MBTL1ALDH1A1 | |
| SCHEMBL8562678 | 0.84 | HPGD (0.49) | KMT2AL3MBTL1GAAALDH1A1 | |
| SCHEMBL1543096 | 0.84 | MEN1 (0.54) | KMT2AGAAALDH1A1MEN1MAPT | |
| SCHEMBL16885994 | 0.84 | KMT2A (0.54) | KMT2AGAAALDH1A1MEN1PKM | |
| SCHEMBL8562675 | 0.84 | HPGD (0.49) | KMT2AL3MBTL1GAAALDH1A1 | |
| SCHEMBL27485082 | 0.83 | NPC1 (0.44) | MMP8KMT2AL3MBTL1MEN1PKM | |
| SCHEMBL526555 | 0.83 | KMT2A (0.53) | MMP8KMT2AMMEL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804577-A | ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1998-09-08 | — | — | US | disclosed |
| EP-0761673-A1 | Cephalosporin derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1997-03-12 | — | — | EP | disclosed |