Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8568795 | 1.00 | MTNR1A (0.48) | MTNR1AMTNR1BEPHX2MEN1KMT2A | |
| SCHEMBL7418106 | 0.82 | MTNR1A (0.55) | MTNR1AMTNR1BEPHX2MEN1KMT2A | |
| SCHEMBL7418105 | 0.82 | MTNR1A (0.55) | MTNR1AMTNR1BEPHX2MEN1KMT2A | |
| SCHEMBL8561678 | 0.82 | MTNR1A (0.55) | MTNR1AMTNR1BEPHX2MEN1KMT2A | |
| SCHEMBL8562997 | 0.77 | MTNR1A (0.50) | MTNR1AMTNR1BEPHX2MEN1KMT2A | |
| SCHEMBL8562991 | 0.77 | MTNR1A (0.50) | MTNR1AMTNR1BEPHX2MEN1KMT2A | |
| SCHEMBL23420616 | 0.76 | MTNR1A (0.55) | MTNR1AMTNR1BEPHX2MEN1KMT2A | |
| SCHEMBL8568800 | 0.76 | MTNR1A (0.49) | MTNR1AMTNR1BEPHX2MEN1KMT2A | |
| SCHEMBL8570073 | 0.75 | MTNR1A (0.42) | MTNR1AMTNR1BEPHX2MEN1KMT2A | |
| SCHEMBL8570063 | 0.75 | MTNR1A (0.42) | MTNR1AMTNR1BEPHX2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719141-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1998-02-17 | — | — | US | disclosed |