Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CLK2 | P49760 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563230 | 0.91 | KCNH2 (0.49) | KCNH2KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL8570302 | 0.91 | KCNH2 (0.61) | KCNH2KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL8573195 | 0.91 | KCNH2 (0.61) | KCNH2KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL8568239 | 0.90 | KCNH2 (0.65) | KCNH2KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL8568234 | 0.90 | KCNH2 (0.65) | KCNH2KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL9690912 | 0.89 | KCNH2 (0.49) | KCNH2KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL8330230 | 0.87 | KCNH2 (0.69) | KCNH2KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL8329727 | 0.87 | KCNH2 (0.69) | KCNH2KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL8564597 | 0.87 | ALDH1A1 (0.60) | KCNH2KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL8571269 | 0.87 | ALDH1A1 (0.60) | KCNH2KDM4EALDH1A1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559752-B1 | OPTICAL ISOMERS OF 7- 3-(1,1-DIALKYLMETHYL-1-AMINO-1-PYRROLIDINYL]-QUINOLONES AND NAPHTHYRIDONES AS ANTIBACTERIAL AGENTS | WARNER LAMBERT CO (US) | 1998-01-28 | — | — | EP | claimed |